Antibody-Binding Proteins and Conjugates
Cayman Chemical RosuvastatIncalcIum salt 50mg
An antimalarial agent active against six P. falciparum drug-sensitive or -resistant strains (IC50s 1.53-3.94 nM) reduces parasitemia in P. chabaudi-infected mice at 3 6 and 8 mg/kg in combination with artesunate inhibits SARS-CoV-2 replication in infected A459-ACE2 cells (IC50 198 nM) cytotoxic against a panel of human cancer cells lines (CC50s 1.6-4.9 UM)
Cayman Chemical CefamndolesodIum salt 50mg
A potent EP4 agonist triggering cAMP signaling with an EC50 value of 0.8 nM
Cayman Chemical DIquafosolsodIum salt 50mg
A trisesquiterpenoid active against E. coli M. phlei P. aeruginosa and S. aureus increases basal HO-1 and Nrf2 activities and inhibits LPS-induced production of IL-6 IL-1B and TNF-a in RAW 264.7 cells at 40 UM reduces escape latency in the Morris water maze and the number of slips in a beam crossing task in a rat model of Huntingtons disease induced by 3-NP at 5 10 and 15 mg/kg a precursor in the formation of PAHs and a synthetic intermediate in the synthesis of coenzyme Q10 and vitamin K analogs that have antioxidant activities
Cayman Chemical MetamIzolesodIum salt 50mg
An oxidized sterol active against the P. falciparum chloroquine-sensitive strain FCA 20/GHA (IC50 8.2 UM) induces apoptosis in LNCaP and DU145 prostate cancer cells from 6.25-50 UM inhibits growth of SNU-1 gastric SNU-354 hepatoma and SNU-C4 colorectal cancer cells (IC50s 18.7 158.2 and 84.6 UM respectively inhibits LPS-induced NF-kB DNA-binding activity and production of TNF-a in RAW 264.7 cells at 60 UM reduces ear edema in a mouse model of inflammation induced by TPA (ID50 0.2 mg/ear)
Cayman Chemical MItIglInIdecalcIum salt 500mg
An HDAC8 inhibitor (IC50 27 2 nM) selective for HDAC8 over HDAC1-3 -4 -6 -10 and -11 (IC50s 3000 nM for all) cytotoxic to A549 H1299 and CL1-5 lung cancer cells (IC50s 7 9 7 2 and 7 M respectively)
Cayman Chemical GluCys ammonium salt 50mg
An inhibitor of Cdk8 and Cdk19 inhibits Cdk8 (IC50s 24-50 nM depending on assay) selectively inhibits Cdk19 and Cdk8 by 98 6 and 97 8 respectively in a panel of 450 kinases at 2 M but does inhibit MAP4K2 and YSK4 by 69 and 59 respectively inhibits cell growth in MCF-7 BT474 and T47D-ER/Luc breast cancer cells in estrogen-containing media at 1 25-5 M reduces tumor growth in an MCF-7 mouse xenograft model at 100 mg/kg twice per day inhibits RANKL-induced differentiation of murine BMDMs into osteoclasts at 1 and 1 5 M increases the bone volume fraction and bone mineral density in injured tibiae in a rat model of cancellous bone injury and regeneration when administered locally at 1 g
Cayman Chemical FosphenytoInsodIum salt 50mg
A histamine H1 receptor antagonist (Ki 62 5 nM) selective for histamine H1 over H2 and H3 receptors (Kis 23 5 and 1 94 UM respectively) binds to the rat neurotensin-2 receptor (IC50 10 nM) reduces the severity of ovalbumin-induced conjunctivitis in ovalbumin-sensitized rats when applied ocularly to ovalbumin-sensitized rats
Cayman Chemical MezlocIlInsodIum salt 500mg
An analytical reference standard that is structurally similar to known phytocannabinoids regulated as a Schedule I compound in the United States intended for research and forensic applications
Bioworld Nanogold*- rabbit (NRI) AB, 0.5 mL
Nanogold* shines when it comes to EM. It is the new gold standard. Nanogold* reagents diffuse easily tens of microns into tissues and into permeabilized cells and cell nuclei, to where most colloidal gold probes have difficulty in reaching.Smallest commer
Biotium Rhodamine Phalloidin, 300U
Phalloidin conjugates are actin filament stains for fixed and permeabilized cells. Red fluorescent rhodamine phalloidin has excitation/emission at 540/565 nm.
Biotium CF430 Tyramide
CF dye tyramide conjugates can be used for tyramide signal amplification (TSA), which is an enzyme-mediated detection method that uses horseradish peroxidase (HRP) to generate high-density labeling of a target protein or nucleic acid in situ. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. 405 nm-excitable green fluorescent CF430 dye has excitation/emission at 426/498 nm.
Jackson Immuno Research Labs AMCA-AffiniPure Goat Anti-Horseradish Peroxidase
AMCA-AffiniPure Goat Anti-Horseradish Peroxidase
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Goat Anti-Horseradish Peroxidase
Rhodamine Red-X-AffiniPure Goat Anti-Horseradish Peroxidase
Jackson Immuno Research Labs DyLight 405-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)
DyLight 405-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)